Fenbendazole 222mg Capsules for Humans
Fenbendazole is an anti-parasitic medication that has been found to also treat cancer in some cases. It works by targeting tumor cells and blocking their growth, as well as disrupting cell division and increasing cellular death. It can be used alone or in combination with other treatments, such as radiation and chemotherapy. It has a wide safety margin and few side effects in humans, making it an excellent drug to test in clinical trials for use in the treatment of cancer.
Cancer is an uncontrollable growth of abnormal cells that forms malignant tumors, which spread throughout the body and attack healthy tissues. Despite advances in medicine and surgery, cancer remains a major cause of death worldwide. The discovery of drugs that can kill cancerous cells while sparing normal cells is needed urgently. A number of promising drugs are currently in development, including a compound called fenbendazole.
In 2008, researchers studying human lymphoma xenografts in mice found that fenbendazole significantly suppressed tumor growth. The scientists attributed this effect to fenbendazole’s ability to block the formation of microtubules in the cancer cells. These microtubules are the structures that hold other parts of the cells together, and preventing them from forming leads to cell cycle arrest and apoptosis.
Another mechanism of fenbendazole’s anti-cancer action is its ability to prevent cancer cells from absorbing glucose, a process known as aerobic glycolysis. Cancer cells use glucose more rapidly than normal cells, using it as a fuel for their uncontrolled growth. This process can be seen on PET scans, where metabolically active areas appear as bright spots on the image. Fenbendazole inhibits this process by binding to cytosolic tubulin dimers and blocking their assembly.
A third way fenbendazole helps fight cancer is by preventing it from developing resistance to other cancer medications. Many types of tumors are able to escape the effect of anti-cancer medicines by pumping them out of the cell through a series of drug efflux pumps. Unlike other drugs, fenbendazole is not a target of these P-glycoproteins, and thus is able to enter the cancer cells without being pumped out by the tumors’ efflux pumps.
Patients should start by taking the basic starter fenbendazole dosage of 222 mg per day for three days, then take four days off. During the off days, patients should continue to monitor their liver enzyme levels and pay attention to how they feel. Some patients may experience flu-like symptoms during this detoxification, such as stomach upset, drooling, a general change in mood, and other discomforts. However, these symptoms should not last more than a few weeks. During this time, it is a good idea to get frequent blood tests to ensure that liver and kidney function are not becoming too stressed by the fenbendazole. If they do, the dosage should be reduced to 2.5 mg so that the liver and kidneys can adjust at a slower pace. fenbendazole 222mg capsules for humans
